Relier Pairs HISTOLOGY: Bones, cartilage, joints, lesson 3Version en ligne MIDTERM par Danillee Faye Mabayag 1 Lamellar bone (Synonyms) 2 Lamellar bone (Location) 3 Woven bone (Major location) 4 Woven bone (Characteristics) 5 Woven bone (SYNONYMS) 6 Lamellar bone (Characteristics) 7 LAMELLAR vs WOVEN BONE Parallel organized collagen in thin layers (lamellae); regularly spaced cells; heavily calcified Immature, Primary, Bundle bone, newly calcified All normal regions in adult bone LAMELLAR vs WOVEN BONE Developing and growing bones; hard callus of bone fractures Mature bone; 2ndary bone Irregular and random collagen. Lightly calcified 1 Cancellous bone (Synonyms) 2 Compact bone (Location) 3 Compact bone (synonyms) 4 Cancellous bone (Characteristics) 5 Compact VS Cancellous bone 6 Cancellous bone (Location) 7 Compact bone (Characteristics) Thick, outer region (beneath periosteum) of bones Parallel lamellae or DENSEpacked osteons, w. interstitial lamellae Inner region of bones, adjacent to marrow cavities 20% of all lamellar bone; Spongy bone; TRABECULAE; bone; Medullary bone Interconnected thin spicules/ trabeculae covered by endosteum Compact VS Cancellous bone 80% of all lamellar bone, Cortical bone 1 Hyaline cartilage (perichondrium) 2 Fibrocartilage 3 Elastic cartilage 4 Fibrocartilage (Type 1 predominant) (Organ) 5 Hyaline cartilage (Type 2)(Organ) 6 Elastic cartilage (Type 2) (Organ) Has perichondrium BRONCHI; TRACHEA; Articular ends and EPIPHYSEAL PLATE of long bones; Fetal skeleton; ARTICULAR and COSTAL cartilage; Intervertebral disc; Pubic symphysis; meniscus; insertion of tendon NO PERICHONDRIUM External EAR; External acoustic meatus, auditory tube'; EPIGLOTTISand other laryngeal cartilage, AURICLE, EUSTACHIAN TUBE Has perichondrium (except epiphyses and articular cartilage) 1 Fibrocartilage (Type 1) 2 Hyaline cartilage (Type 2) 3 Elastic cartilage (Type 2) Type 1 predominantly but has small type 2, cushion, tensile strength and resistance to tear Flexible , dark elastic fibers, aggrecan Glassy, smooth, homogenous, structural support, low friction surface in joints; respiratory tract, aggrecan 1 4 REGIONS in ELECTRON MICROSCOPY 2 Basal zone 3 Vesicular zone 4 Clear zone 5 Ruffled border Attachment/sealing ; MICROFILAMENTS 4 REGIONS in ELECTRON MICROSCOPY opposite of ruffled border; MOST CELL ORGANELLES Exocytotic vesicles (transfer lysosomal enzymes) ; Endocytotic vesicles (transfer degraded bone); Enzyme product transport Active bone RESORPTION (irregular finger like cytoplasmic extend to Howship) 1 Hypertrophic zone 2 2NDARY CENTER OF OSSIFICATION 3 Calcified zone 4 Ossification zone 5 Proliferative zone 6 Resting zone Bone tissue first appears (osteoblast lay bone) 2NDARY CENTER OF OSSIFICATION Hyaline cartilage loss of chondrocytes + calcification Chondrocytes DIVIDE into columns swollen, enlarged degenerative chondrocytes 1 Osteoclast 2 Osteoprogenitor 3 Osteocyte 4 Osteoblast builds bone; Cuboidal, basophilic, osteoid nearby; like PLASMA CELL; ECCENTRIC NUCLEUS Resorbs bone; Large, MULTINUCLEATED, howship lacunae; DESTRUCTION Stem/precursor cell; Gives rise to osteoblast Maintains bone; In lacunae, processes in canaliculi' Regular spaced matrix; flat-almond shape, less RER 1 Secondary center 2 Volkmann canals 3 Periosteum 4 Osteon 5 Osteocalcin 6 Endochondral 7 Type 2 collagen 8 Type 1 collagen 9 M-CSF and RANKL 10 Primary center 11 Intramembranous Diaphysis Most long bones; primary center in diaphysis, secondary center in epiphysis Hyaline + elastic cartilage Bone + fibrocartilage Epiphysis Flat skull bones Nourish osseous tissue (oppositional bone growth + trabeculae) 2 polypeptides produced by osteoblast Complex; haversian system Noncollagen secreted by osteoblast rich in ALP; serve as foci for HYDROXYAPATITE CRYSTAL Perforating canals 1 Type 1 collagen, proteoglycan aggregates; bone-specific multiadhesive glycoproteins 2 Howship lacunae or Resorption cavity 3 Cement line 4 Calcium hydroxyapatite 5 Regulates hyaline cartilage 6 Concentric lamellae 7 Osteon (Haversian system) 8 Articular cartilage Organic matter composed of Movable joints; lacks perichondrium; diffusion of O2 and nutrients Outer boundary of each osteon complex of concentric lamellae; bifurcated cylinder supporting structure; an osteon (haversian system) Growth hormone and somatotropin (indirect, insuline like) and somatomedins (direct proliferation) areas of bone undergoing resorption, osteoclast lie in depression or cavities Most abundant in bone matrix 1 Syndesmose 2 Symphyses 3 Synostoses 4 Diarthroses 5 Synarthroses United only by bone tx and no movement; SUTURES, thin layers of CT w/ osteogenic cells Very limited or no movement Join bones by dense CT only; INTEROSSEOUS LIGAMENT of inferior tibiofibular joint and posterior SARCROILIAC joints Immobile joints w/ pad of fibrocartilage between articular cartilage; ALL SYMPHYSES, PUBIC SYMPHYSIS, usually in midline Free bone movement; Synovial fluid is made up of HYALURONAN