Relier Pairs Pharm 231 neuropsych, OB, V/M, blood and blood productsVersion en ligne matching drug, indications, class, adverse reactions and interactions par Amanda 1 Methylphenidate (Ritalin): ADHD 2 Lithium: Acute manic episodes and maintenance of bipolar disorder 3 Phenobarbital: Anxiety, insomnia, and seizure disorders 4 Benztropine: Parkinson’s symptoms (tremors, rigidity, drooling) 5 Haloperidol & Quetiapine: Schizophrenia, acute psychosis, and manic episodes of bipolar disorder 6 Phenytoin, Ethosuximide, Divalproex, & Carbamazepine: 7 Diazepam: Severe anxiety, alcohol withdrawal, seizure disorders, and insomnia 8 Ethosuximide and Divalproex: seizures 9 Sertraline (SSRI), & Duloxetine (SNRI): Depression, anxiety, and neuropathic pain 10 Bupropion: Depression and smoking cessation 11 Amitriptyline: Depression, anxiety, and neuropathic pain 12 Carbidopa-Levodopa: Parkinson’s disease 13 Phenytoin: seizures 14 Phenelzine (MAOI): Resistant depression (Dopaminergic): Anxiety, nervousness, and cardiovascular effects (Antimanic): Slurred speech/tremors (<1.5 mEq/L) progressing to seizures and death (>2.5 mEq/L) (TCA): Sedation, suicidality, and anticholinergic effects (Hydantoin): CNS suppression, gingival hyperplasia, and liver damage (Benzodiazepine): CNS depression and paradoxical hyperexcitability in the elderly (MAOI): Hypertensive emergency (CNS Stimulant): Sudden cardiac death in children with cardiac defects (Antipsychotics): Extrapyramidal symptoms (EPS), Neuroleptic Malignant Syndrome (NMS), weight gain, and QT prolongation (NDRI): CNS hyperactivity, weight loss, and suicidality (Anticholinergic): Dry mouth, constipation, and blurred vision (Barbiturate): Severe CNS and respiratory depression Sertraline and Duloxetine (SSRI/SNRI): Serotonin syndrome, loss of libido, and suicidality (Antiepileptics): Bone marrow suppression, liver damage, and severe rashes Various types of seizure disorders (focal, generalized, status epilepticus, or absence) 1 Biktarvy, Penicillin G, Azithromycin, & Metronidazole: Treatment of gestational infections (HIV, GBS, syphilis, chlamydia, gonorrhea, trichomoniasis) 2 Magnesium Sulfate: Prevention of seizures in preeclampsia/eclampsia and fetal neuroprotection 3 Methylergonovine: Sustained uterine contraction for control of PPH 4 Labetalol: Gestational hypertension and preeclampsia 5 Insulin: Management of gestational diabetes 6 Nifedipine & Terbutaline: Tocolytics used to suppress preterm labor contractions 7 Oxytocin: Induction of labor and control of postpartum hemorrhage (PPH) (Pancreatic Hormone): Hypoglycemia and hypokalemia (Oxytocics): Uterine hypertonicity, uterine rupture, and maternal water intoxication Biktarvy (Antiviral): Lactic acidosis and nephrotoxicity (Tocolytics): Hypotension and tachycardia; pulmonary edema (terbutaline only) Uterine hypertonicity, uterine rupture (CNS Depressant): Magnesium toxicity (loss of DTRs, RR <12, CNS depression) (Beta Blocker): Hypotension and bradycardia 1 Flaxseed: Constipation and dyslipidemia 2 Echinacea: May interfere with immunosuppressant drugs 3 St. John’s Wort: Depression 4 Coenzyme Q-10: Mitochondrial encephalomyopathies, CHF, and statin-induced myopathy 5 Cranberry: UTI prevention 6 Garlic: Cardiovascular health (BP/cholesterol) and antimicrobial effects; Ginger: Vertigo, nausea, and anti-inflammatory needs Immunostimulant for flu prevention; contraindicated in pt's taking immunosuppressant drugs can decrease anticoagulant effects of warfarin; decreased BP when combined with antihypertensives, risk of hypoglycemia with insulin Serotonin syndrome and multiple drug interactions Increased risk of bleeding GI adverse effects and decreased absorption of other medications May increase INR with warfarin therapy 1 Potassium: 2 Drug-Drug Interactions of minerals: 3 Sodium: 4 magnesium: 5 Phosphorus: 6 Calcium: 7 Absorption Issues: Used for replacement and to help prevent calcium-based kidney stones by binding to calcium in the intestines osteoporosis and PTH deficiencies. Cardioprotection by stabilizing cardiac membranes (especially in hyperK+), reversal agent for mag toxicity antacid, laxative, first-line treatment for Torsades(polymorphic VT),decreases uterine contractions and prevents seizures in preeclampsia Used for fluid balance and replacement. Imbalances are a primary concern for central nervous system function and can lead to seizures Calcium and magnesium can interfere with the absorption of iron and certain antibiotics, such as tetracyclines electrical excitability in skeletal and cardiac muscle; imbalances often first appear as T-wave changes on telemetry, used for pts on lasix(furosemide Potassium given with potassium-sparing diuretics (e.g., spironolactone) significantly increases the risk of life-threatening hyperkalemia 1 Albumin indications: 2 Nursing Safety Protocols for Blood Products: verification 3 Whole Blood 4 Nursing Safety Protocols for Blood Products: pre-administration 5 Packed Red Blood Cells (PRBCs) 6 Platelets 7 Fresh Frozen Plasma (FFP) 8 Nursing Safety Protocols for Blood Products: Administration: Thrombocytopenia or active bleeding with a low platelet count prime tubing with only 0.9%NS, stay with pt for first 15 min of infusion, transfusion must be completed within 4hrs of leaving the blood bank Active bleeding, DIC, burns, shock, and emergent reversal of warfarin; it is rich in clotting factors Requires a two-nurse check at the bedside to verify the patient's identity and match the unit number and blood type to the order Severe anemia or hemoglobinopathies; used specifically to increase oxygen-carrying capacity informed consent, type and screen (cross-match), except when O-neg is used; use at least a 20-gauge IV (smaller causes hemolysis) Massive blood loss from trauma or surgery; replaces all components (cells and plasma) simultaneously Hypovolemia, hypoalbuminemia, and burns; it provides oncotic pressure to pull fluid into the vasculature
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