Relier Pairs Pharm 231 neuropsych, OB, V/M, blood and blood productsVersion en ligne matching drug, indications, class, adverse reactions and interactions par Amanda 1 Diazepam: Severe anxiety, alcohol withdrawal, seizure disorders, and insomnia 2 Haloperidol & Quetiapine: Schizophrenia, acute psychosis, and manic episodes of bipolar disorder 3 Carbidopa-Levodopa: Parkinson’s disease 4 Phenytoin: seizures 5 Benztropine: Parkinson’s symptoms (tremors, rigidity, drooling) 6 Bupropion: Depression and smoking cessation 7 Amitriptyline: Depression, anxiety, and neuropathic pain 8 Phenytoin, Ethosuximide, Divalproex, & Carbamazepine: 9 Phenelzine (MAOI): Resistant depression 10 Phenobarbital: Anxiety, insomnia, and seizure disorders 11 Lithium: Acute manic episodes and maintenance of bipolar disorder 12 Sertraline (SSRI), & Duloxetine (SNRI): Depression, anxiety, and neuropathic pain 13 Ethosuximide and Divalproex: seizures 14 Methylphenidate (Ritalin): ADHD (Antimanic): Slurred speech/tremors (<1.5 mEq/L) progressing to seizures and death (>2.5 mEq/L) (MAOI): Hypertensive emergency (Anticholinergic): Dry mouth, constipation, and blurred vision (Antiepileptics): Bone marrow suppression, liver damage, and severe rashes Various types of seizure disorders (focal, generalized, status epilepticus, or absence) (Dopaminergic): Anxiety, nervousness, and cardiovascular effects (Hydantoin): CNS suppression, gingival hyperplasia, and liver damage (Antipsychotics): Extrapyramidal symptoms (EPS), Neuroleptic Malignant Syndrome (NMS), weight gain, and QT prolongation (Barbiturate): Severe CNS and respiratory depression (TCA): Sedation, suicidality, and anticholinergic effects Sertraline and Duloxetine (SSRI/SNRI): Serotonin syndrome, loss of libido, and suicidality (CNS Stimulant): Sudden cardiac death in children with cardiac defects (Benzodiazepine): CNS depression and paradoxical hyperexcitability in the elderly (NDRI): CNS hyperactivity, weight loss, and suicidality 1 Labetalol: Gestational hypertension and preeclampsia 2 Biktarvy, Penicillin G, Azithromycin, & Metronidazole: Treatment of gestational infections (HIV, GBS, syphilis, chlamydia, gonorrhea, trichomoniasis) 3 Oxytocin: Induction of labor and control of postpartum hemorrhage (PPH) 4 Methylergonovine: Sustained uterine contraction for control of PPH 5 Insulin: Management of gestational diabetes 6 Nifedipine & Terbutaline: Tocolytics used to suppress preterm labor contractions 7 Magnesium Sulfate: Prevention of seizures in preeclampsia/eclampsia and fetal neuroprotection (Tocolytics): Hypotension and tachycardia; pulmonary edema (terbutaline only) Biktarvy (Antiviral): Lactic acidosis and nephrotoxicity (CNS Depressant): Magnesium toxicity (loss of DTRs, RR <12, CNS depression) Uterine hypertonicity, uterine rupture (Oxytocics): Uterine hypertonicity, uterine rupture, and maternal water intoxication (Beta Blocker): Hypotension and bradycardia (Pancreatic Hormone): Hypoglycemia and hypokalemia 1 St. John’s Wort: Depression 2 Cranberry: UTI prevention 3 Flaxseed: Constipation and dyslipidemia 4 Echinacea: May interfere with immunosuppressant drugs 5 Garlic: Cardiovascular health (BP/cholesterol) and antimicrobial effects; Ginger: Vertigo, nausea, and anti-inflammatory needs 6 Coenzyme Q-10: Mitochondrial encephalomyopathies, CHF, and statin-induced myopathy May increase INR with warfarin therapy Immunostimulant for flu prevention; contraindicated in pt's taking immunosuppressant drugs Increased risk of bleeding GI adverse effects and decreased absorption of other medications Serotonin syndrome and multiple drug interactions can decrease anticoagulant effects of warfarin; decreased BP when combined with antihypertensives, risk of hypoglycemia with insulin 1 Phosphorus: 2 Drug-Drug Interactions of minerals: 3 Potassium: 4 Calcium: 5 Sodium: 6 Absorption Issues: 7 magnesium: Used for replacement and to help prevent calcium-based kidney stones by binding to calcium in the intestines Used for fluid balance and replacement. Imbalances are a primary concern for central nervous system function and can lead to seizures Calcium and magnesium can interfere with the absorption of iron and certain antibiotics, such as tetracyclines electrical excitability in skeletal and cardiac muscle; imbalances often first appear as T-wave changes on telemetry, used for pts on lasix(furosemide antacid, laxative, first-line treatment for Torsades(polymorphic VT),decreases uterine contractions and prevents seizures in preeclampsia osteoporosis and PTH deficiencies. Cardioprotection by stabilizing cardiac membranes (especially in hyperK+), reversal agent for mag toxicity Potassium given with potassium-sparing diuretics (e.g., spironolactone) significantly increases the risk of life-threatening hyperkalemia 1 Nursing Safety Protocols for Blood Products: verification 2 Nursing Safety Protocols for Blood Products: Administration: 3 Platelets 4 Packed Red Blood Cells (PRBCs) 5 Whole Blood 6 Fresh Frozen Plasma (FFP) 7 Nursing Safety Protocols for Blood Products: pre-administration 8 Albumin indications: Thrombocytopenia or active bleeding with a low platelet count Severe anemia or hemoglobinopathies; used specifically to increase oxygen-carrying capacity Hypovolemia, hypoalbuminemia, and burns; it provides oncotic pressure to pull fluid into the vasculature Active bleeding, DIC, burns, shock, and emergent reversal of warfarin; it is rich in clotting factors prime tubing with only 0.9%NS, stay with pt for first 15 min of infusion, transfusion must be completed within 4hrs of leaving the blood bank Requires a two-nurse check at the bedside to verify the patient's identity and match the unit number and blood type to the order informed consent, type and screen (cross-match), except when O-neg is used; use at least a 20-gauge IV (smaller causes hemolysis) Massive blood loss from trauma or surgery; replaces all components (cells and plasma) simultaneously
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