Relier Pairs AsepticVersion en ligne Week 1,2,3 par Audree Dulnuan 1 Low-risk BUD at controlled room tempt 2 High risk BUD at controlled room tempt 3 Medium risk BUD at controlled room tempt 4 Sterile unit 5 Low risk with storage in refrigerator 6 High risk level 7 High risk with storage in refrigerator 8 Low risk level 9 Medium risk with storage in refrigerator 10 BUD with storage in freezer for all risks 11 Medium risk level 12 Sterility test & bacterial endotoxin test Using up to 3 "sterile units," no more than 2 "septum" punctures for one patient & it is a simple transfer. Using 4 or more "sterile units" (reconstituted products), complex, prolonged preparation time, compounding more than 1 item of the same drug in 1 sesh 14 days 48 hours Germ-free enclosures: IV bag, vials, ampoules Must be performed for high-risk sterile preparations, if over 25 identical units, hrs exposure between 2-8 degrees, 6 hrs exposure above 8 degrees. 24 hours 45 days 30 hours 3 days 9 days Non-sterile products are being compounded before they are sterilized, using water, stored for more than 6 hours, and improperly donned. 1 Compounding for sodium-free diet, or healthy heart diet 2 Pathogenic 3 CSHP 4 Compounding order for a IV bags 5 Rate of infusion 6 Fluid Restricted patient 7 Particulate matter 8 RSI 9 Compounding an order for a diabetic patient 10 How long should you wash your eyes using emergency eyewash? 11 Pyrogens 12 NAPRA NaCl Sodium Chloride 0.9% 50 mL Materials like hair, lint, dust, cotton, fur, undissolved drug. They are bough or introduce into the prdocut by compounding person. Default to Sodium Chloride 0.9%, volume reflective of the order or default default to 25 mL solution D5W Dextrose 5% in Water capable of causing disease, or a organism capable causing disease in it;s host National Association of Pharmacy Regulatory Authorities 15 minutes The Canadian Society of Hospital Pharmacists Repetitive Strain Injury Only drug preparations with IV route, IVPB, IV push Metabolic by-products of microorganisms which, when injected into the bloodstream, can produce a febrile reaction 1 Intra-articular 2 Intramuscular 3 Particulate contamination 4 Intrathecal 5 Intraocular 6 Cross contamination 7 Intravenous 8 Shadowing 9 Intraosseous 10 Subcutaneous 11 Intraperitoneal 12 Microbial contamination 13 Intradermal 14 Epidural 15 Critical site Into the cerebrospinal fluid surrounding the spinal cord, drugs affecting the CNS Into the abdominal cavity, used for certain chemotherapy or in animal research Foreign chemical, microbial, or physical substances are unintentionally transferred from one substance or object to medicines. Presence of extraneous, mobile/undissolved particles in parenteral solution. Great & severe risk. Blockages of blood vessels, organ damage, phlebitis It is simply when you block the clean airflow to a medication or product. Into the bone-marrow, usually emergency access route when IV fails, common in pediatrics/trauma Directly into a joint space, delivering anti-inflammatory drugs Inclusion or growth of harmful microorganisms which include mold, yeast, and viruses & bacteria Injecting medication into the fatty tissue just beneath the skin dermis provides slow & steady absorption due to fewer blood vessel, insulin, hormones Directly into the eye Delivering fluids, medications, nutrition, or blood directly into a patient's vein using a thin plastic tube Similar to intrathecal, but into the epidural space around the spinal cord (common for childbirth) Injecting medication deep into muscle tissue, allowing for rapid absorption into the bloodstream due to muscles' rich blood supply, 90 degree angle A shallow injection into the dermis, the layer just below the epidermis, using a small needle at a 5-15 degree angle, for anesthesia, TB, allergy Any location that is exposed & can allow intrusion of microorganisms or foreign matter. 1 Horizontal PEC 2 Cleaning the PEC 3 The cleanroom (CIVA or IV room) 4 Anteroom 5 Vertical PEC 6 Aseptic Technique 7 USP 800 8 ISO class 9 ABHR 10 PEC Primary Engineering Control Unit Class B environment, ISO 7 class, positively pressured unless cytotoxic, HEPA filter, 30 or more air changes per hour, no greater than 20 degrees Where hazardous compounding area is done, negative pressure Process & physical preparation methods, who prepares sterile compounds, to prevent pathogenic organisms from contaminating a sterile environment Alcohol-based hand rub Do not obstruct airflow, no protection, aerosol can be blown towards the operator, procedures 15 cm. Germicidal, disinfecting detergent, sterile 70% alcohol, The International organization for Standardization, defines the amount of particulate matter in room air, ranges class 3 to 8 class Class C environment, ISO class 8, pressurized by positive air, used for garbing, hand hygiene, labelling & staging components. Air moves from top to bottom and provides protection. Procedures are 7.5 cm; work at 45-degree angle. 1 Stability for IV bag once punctured inside the PEC room 2 Continuous Infusion 3 Laminar Air (LAFW) 4 Intermittent infusion 5 Central injection route 6 HEPA filter 7 Peripheral injection route 8 SC neelde/syringe 9 IVPush 10 IM needle/ syringe Drugs can be administered over a specific period of time at intervals & can be infused through a primary line. 5 mL syringe, 19-gauge needle, dose: do not pull back, small volume into vein, given for short period of time, supplied in syringe Allows a carefully regulated amount of fluid to be given over a long period of time, maintain a constant drug level, uses gravity to help infusion. 1 mL syringe, 25-gauge needle, dose pull back provides clean air to the working area, constant flow, removes contaminants, bacteria, repetitive filter 3 mL syringe, 21-gauge needle, dose pull back High-Efficiency Particulate Air Filter Needs to be surgically inserted into the heart, through the large vein to superior vena cava, inferior vena cava, right atrium of the heart catheter inserted through skins into peripheral vein Good for 6hrs