DNA Damage Repair Quiz

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Test your DSB repair know-how.

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Aliyah Amparan

United States

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Froggy Jumps DNA Damage Repair QuizVersion en ligne Test your DSB repair know-how. par Aliyah Amparan 1 Which repair pathway is fastest but most error-prone for DSBs in G1? a NHEJ b HR c TLS 2 What marks the DSB site and helps recruit repair proteins? a γ-H2AX b PCNA c RPA 3 Which repair pathway uses a sister chromatid as a template? a Alt-EJ b NHEJ c HR 4 Alt-EJ relies on what short sequences to rejoin ends? a direct ligation b blunt ends c microhomology 5 What enzyme complex initiates NHEJ by binding DSB ends? a MRN complex b Ku70/80 c Rad51 6 Which polymerase is often involved in TLS to bypass lesions? a Pol eta b Pol delta c Pol beta 7 Which checkpoint kinases halt the cell cycle after a break? a CDK1/2 b ERK1/2 c ATM/ATR 8 What happens to DNA ends during Alt-EJ leading to deletions? a ligation without processing b resection and microhomology pairing c direct ligation 9 DSBs form most dangerously during which cellular process? a Transcription b Translation c DNA replication 10 What can TLS be mutagenic to tolerate damage? a Only in bacteria b Yes, it's error-prone c No, it's error-free

Froggy Jumps

DNA Damage Repair QuizVersion en ligne

Test your DSB repair know-how.

par Aliyah Amparan

Which repair pathway is fastest but most error-prone for DSBs in G1?

NHEJ

TLS

What marks the DSB site and helps recruit repair proteins?

γ-H2AX

PCNA

RPA

Which repair pathway uses a sister chromatid as a template?

Alt-EJ

NHEJ

Alt-EJ relies on what short sequences to rejoin ends?

direct ligation

blunt ends

microhomology

What enzyme complex initiates NHEJ by binding DSB ends?

MRN complex

Ku70/80

Rad51

Which polymerase is often involved in TLS to bypass lesions?

Pol eta

Pol delta

Pol beta

Which checkpoint kinases halt the cell cycle after a break?

CDK1/2

ERK1/2

ATM/ATR

What happens to DNA ends during Alt-EJ leading to deletions?

ligation without processing

resection and microhomology pairing

direct ligation

DSBs form most dangerously during which cellular process?

Transcription

Translation

DNA replication

What can TLS be mutagenic to tolerate damage?

Only in bacteria

Yes, it's error-prone

No, it's error-free

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DNA Damage Repair Quiz

Froggy Jumps

À propos de cette activité

Créé par

Téléchargez la version pour jouer sur papier

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Froggy Jumps

DNA Damage Repair QuizVersion en ligne

par Aliyah Amparan

Which repair pathway is fastest but most error-prone for DSBs in G1?

What marks the DSB site and helps recruit repair proteins?

Which repair pathway uses a sister chromatid as a template?

Alt-EJ relies on what short sequences to rejoin ends?

What enzyme complex initiates NHEJ by binding DSB ends?

Which polymerase is often involved in TLS to bypass lesions?

Which checkpoint kinases halt the cell cycle after a break?

What happens to DNA ends during Alt-EJ leading to deletions?

DSBs form most dangerously during which cellular process?

What can TLS be mutagenic to tolerate damage?

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