Relier Pairs GI drug Matching!!Version en ligne Match the drug to its class, MOA, adverse effect and more par Tamia Witherspoon 1 Docusate 2 Metoclopramide 3 Sucralfate 4 Alosetron 5 Omeprazole 6 Sodium bicarbonate 7 Senna 8 Psyllium 9 Misoprostol 10 cimetidine 11 Pancrelipase 12 Loperamide 13 Methylnaltrexone bromide 14 Magnesium citrate Antacids Prostaglandin IBS and Chronic Constipation drugs Osmotic Laxatives Protein pump inhibitors Bulk-Forming Laxatives Antidiarrheal Opioid Antagonist Gastrointestinal protect Chemical stimulants laxatives Lubricants GI Stimulants histamine-2 antagonist Drug used to treat digestive enzyme dysfunction 1 Methylnaltrexone bromide 2 Misoprostol 3 Loperamide 4 Omeprazole 5 Alosetron 6 Psyllium 7 Sodium bicarbonate 8 Sucralfate 9 Senna 10 Pancrelipase 11 Docusate 12 Metoclopramide 13 Magnesium citrate 14 Cimetidine Accelerates gastric emptying Lowers gastric acid secretion Neutralizes stomach acid Inhibits peristalsis & prolongs transit time. Combines w/ water in intestines to soften stool & increase bulk Rises firmness in stool & lowers urgency Lowers stomach acid secretion, raises production of protective mucus & bicarbonate = causes uterine contractions Forms a thick paste w/ stomach acid that adheres to ulcers Stimulates peristalsis Blocking opioid receptors in the GI tract w/out affecting pain relief in the brain. Restores normal bowel movement & secretion. Draws water into intestine, promotes peristalsis Draws water into stool, resulting in softer stool Facilities the digestion of fat, carbohydrates, and protein in the GI tract Blocks H2 receptors in the stomach, reducing gastric acid secretion 1 Loperamide 2 Cimetidine 3 Senna 4 Pancrelipase 5 Omeprazole 6 Docusate 7 Sucralfate 8 Misoprostol 9 Metoclopramide 10 Psyllium 11 Alosetron 12 Magnesium citrate 13 Sodium bicarbonate 14 Methylnaltrexone bromide Cardiac arrest, Gynecomatia, Somnolence C.diff, bone fractures, magnesium, calcium, B12 deficiency Constipation, Vertigo, Insomnia, Indigestion Constipation, Diarrhea, Fluid retention, Electrolyte issues Mild cramping, nausea, vomiting. Toxic megacolon (rare but serious), Severe abdominal pain or diarrhea➡️may indicate GI perforation or need for dose reduction/discontinuation Hyper magnesium, cramping, bloating, diarrhea. Diarrhea, Nausea, Abdominal pain Cathartic dependence Constipation, ischemic colitis Mild cramping, Frequent use can interfere w/ the absorption of fat-soluble vitamins A, D, E, & K long term use=deficiency. Rigidity, tremors, restlessness. Tardive dyskinesia, seizures, Parkinson’s-like symptoms, low BP & HR ( due to parasympathetic stimulation) Dysmenorrhea (painful & severe menstrual cramps), irregular periods (hypermenorrhea), miscarriage 1 Prostaglandin 2 Loperamide 3 Sucralfate 4 Omeprazole 5 Psyllium 6 Senna 7 Alosetron 8 Pancrelipase 9 Docusate 10 Cimetidine 11 Sodium bicarbonate 12 Metoclopramide 13 Magnesium citrate 14 Methylnaltrexone bromide Constipation, bowel prep before a surgery or procedure. Prevention of gastric ulcers in pts taking NSAIDs. Also induces labor by ripening the cervix. Duodenal & gastric ulcers, GERD, Zollinger-Ellison syndrome Pancreatic insufficiency related to pancreatitis, cystic fibrosis, GI bypass surgery. Constipation, prevention of straining, and management of chronic watery diarrhea. Duodenal & gastric ulcers, GERD Zollinger-Ellison Relieve different levels of diarrhea (acute, chronic, irritable bowel syndrome (IBS), reducing ileostomy discharge IBS w/ diarrhea Chronic noncancer pain Peptic ulcer disease, GERD Gastroparesis, Nausea, vomiting GERD. Draws water into stool, resulting in softer stool. Short term treatment of constipation. Bowel prep before surgery or procedure. Duodenal ulcers 1 Cimetidine 2 Loperamide 3 Metoclopromide 4 Senna 5 Psyllium 6 Sodium Bicarbonate 7 Pancrelipase 8 Magnesium citrate 9 Alosetron 10 Docusate 11 Sucralfate 12 Omeprazole 13 Methylnaltrexone bromide Symptom managing, not a cure, hydration and dietary fiber as tolerated Swallow whole!, report diarrhea, abdominal pain, and bloody stools. Take before meals preferably in the morning. Try using only for short-term Increase fluids, fiber, & activity. Don’t use daily to avoid dependence, report severe abdominal pain or persistent constipation. Take immediately before or w/ meals & snacks, swallow whole!, if pill is difficult to swallow open pill & sprinkle on acidic food. Take w/ a full glass of water, increase fiber & fluid intake, short term use only, results may take several days. Fluid & electrolyte replacement during diarrhea episodes. Avoid bismuth in children or teens w/ viral infections. Report severe abdominal pain, nausea, or diarrhea. Hydration & diet changes to promote natural bowel motility. Take w/ a full glass of water, increase fiber, fluid, & exercise, don’t take before bedtime, report persistent constipation or abdominal pain. Take after meals & at bedtime, 1-2 hrs. before or after other medications. Always follow label directions carefully, report prolonged diarrhea or cramping, short term relief only, raise adequate fluid intake. Don’t Double up, report black/tarry stools, avoid caffeine, and take before meals or at bedtime Report unusual facial or body movements, restlessness, or muscle stiffness immediately. Take 1 hr before meals & at bedtime (4 times a day), increase fluid & fiber intake, swallow whole!
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