PGx Week 7 Practice Quiz: CYP2D6

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CYP2D6 Part 1: Opioid analgesics and antidepressants

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Sophia

United States

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PGx Week 7 Practice Quiz: CYP2D6Version en ligne CYP2D6 Part 1: Opioid analgesics and antidepressants par Sophia 1 Which of the following antidepressants is affected by CYP2D6 polymorphisms? a Sertraline (Zoloft) b Paroxetine (Paxil) c Bupropion (Wellbutrin) d Escitalopram (Lexapro) 2 Determine the CYP2D6 activity score(s) for a patient with genotype 1/10xN. (1 has an activity score of 1, 10 has an activity score of 0.25).Select all that apply. Choose one or more answers a 0 b 1 c 1.25 d 1.5 e 2.25 f 3 3 Which of the following analgesics are affected by CYP2D6 polymorphism? Select all that apply. Choose one or more answers a Codeine b Hydrocodone c Hydromorphone d Morphine 4 Patient TN is being prescribed an opioid analgesic for pain management following an orthopedic surgery. TN has a CYP2D6 phenotype of ultra-rapid metabolizer. What would be the outcome if she was prescribed label recommended dose of tramadol? a TN would experience adequate analgesic response with a standard risk of toxicity. b TN would experience inadequate pain relief. c TN would experience a higher risk of toxicity. 5 Patient TN has a CYP2D6 activity score of 3 and a phenotype of ultra-rapid metabolizer. Her PCP would like to start her on an antidepressant. What would you tell TN's provider if they recommended label recommended dose of paroxetine? a Select an alternative antidepressant not metabolized by CYP2D6. b Initiate therapy with recommended starting dose. c Consider a lower starting dose and slower titration. d Consider a 50% reduction in starting dose, slower titration, and a 50% lower maintenance dose.

PGx Week 7 Practice Quiz: CYP2D6Version en ligne

CYP2D6 Part 1: Opioid analgesics and antidepressants

par Sophia

Which of the following antidepressants is affected by CYP2D6 polymorphisms?

Sertraline (Zoloft)

Paroxetine (Paxil)

Bupropion (Wellbutrin)

Escitalopram (Lexapro)

Determine the CYP2D6 activity score(s) for a patient with genotype 1/10xN. (1 has an activity score of 1, 10 has an activity score of 0.25).Select all that apply.

Choose one or more answers

1.25

1.5

2.25

Which of the following analgesics are affected by CYP2D6 polymorphism? Select all that apply.

Choose one or more answers

Codeine

Hydrocodone

Hydromorphone

Morphine

Patient TN is being prescribed an opioid analgesic for pain management following an orthopedic surgery. TN has a CYP2D6 phenotype of ultra-rapid metabolizer. What would be the outcome if she was prescribed label recommended dose of tramadol?

TN would experience adequate analgesic response with a standard risk of toxicity.

TN would experience inadequate pain relief.

TN would experience a higher risk of toxicity.

Patient TN has a CYP2D6 activity score of 3 and a phenotype of ultra-rapid metabolizer. Her PCP would like to start her on an antidepressant. What would you tell TN's provider if they recommended label recommended dose of paroxetine?

Select an alternative antidepressant not metabolized by CYP2D6.

Initiate therapy with recommended starting dose.

Consider a lower starting dose and slower titration.

Consider a 50% reduction in starting dose, slower titration, and a 50% lower maintenance dose.

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PGx Week 7 Practice Quiz: CYP2D6

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PGx Week 7 Practice Quiz: CYP2D6Version en ligne

par Sophia

Which of the following antidepressants is affected by CYP2D6 polymorphisms?

Determine the CYP2D6 activity score(s) for a patient with genotype 1/10xN. (1 has an activity score of 1, 10 has an activity score of 0.25).Select all that apply.

Choose one or more answers

Which of the following analgesics are affected by CYP2D6 polymorphism? Select all that apply.

Choose one or more answers

Patient TN is being prescribed an opioid analgesic for pain management following an orthopedic surgery. TN has a CYP2D6 phenotype of ultra-rapid metabolizer. What would be the outcome if she was prescribed label recommended dose of tramadol?

Patient TN has a CYP2D6 activity score of 3 and a phenotype of ultra-rapid metabolizer. Her PCP would like to start her on an antidepressant. What would you tell TN's provider if they recommended label recommended dose of paroxetine?

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PGx Week 7 Practice Quiz: CYP2D6

Test

À propos de cette activité

Créé par

Téléchargez la version pour jouer sur papier

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Practice Quiz - Punnett Square, Variation, and Mutations

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PGx Week 7 Practice Quiz: CYP2D6Version en ligne

par Sophia

Which of the following antidepressants is affected by CYP2D6 polymorphisms?

Determine the CYP2D6 activity score(s) for a patient with genotype *1/*10xN. (*1 has an activity score of 1, *10 has an activity score of 0.25).Select all that apply.

Which of the following analgesics are affected by CYP2D6 polymorphism? Select all that apply.

Patient TN is being prescribed an opioid analgesic for pain management following an orthopedic surgery. TN has a CYP2D6 phenotype of ultra-rapid metabolizer. What would be the outcome if she was prescribed label recommended dose of tramadol?

Patient TN has a CYP2D6 activity score of 3 and a phenotype of ultra-rapid metabolizer. Her PCP would like to start her on an antidepressant. What would you tell TN's provider if they recommended label recommended dose of paroxetine?

Determine the CYP2D6 activity score(s) for a patient with genotype 1/10xN. (1 has an activity score of 1, 10 has an activity score of 0.25).Select all that apply.