COVID-19: Molecular Entry Puzzle

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Spot the cellular doorway the virus targets.

Créé par

Mohammed Zahir Khan

Kazakhstan

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COVID-19: Molecular Entry Puzzle


COVID-19: Molecular Entry PuzzleVersion en ligne Spot the cellular doorway the virus targets. par Mohammed Zahir Khan 1 A doorway on human cells that the virus seeks to open. Hints 1 Serves as the cellular receptor exploited by SARS-CoV-2. 2 Expressed in tissues such as the lungs and intestines. 3 It's a host protein used by the virus to enter cells. 2 A simple act that helps stop germs from spreading. Hints 1 A widely promoted public health habit to reduce transmission. 2 Do this after using the bathroom, after coughing or sneezing, and before eating. 3 Wet hands, apply soap, and rub for at least 20 seconds. 3 A tiny invader with a crown-like appearance that started a global crisis. Hints 1 First identified in late 2019, Wuhan, China. 2 It binds to ACE2 receptors via a spike protein. 3 Causes a disease named COVID-19. 4 A specific protein on my surface helps me attach to human cells and enter them. Hints 1 A major target for vaccines and antibodies. 2 Interacts with a receptor to gain entry into cells. 3 Forms the characteristic crown-like appearance under a microscope. 5 I reside on the cell surface, acting as the doorway that SARS-CoV-2 uses to gain entry. Hints 1 Also involved in regulating blood pressure. 2 Binds the viral spike protein to facilitate entry. 3 A receptor found on many human cells, including lungs. 6 An antiviral drug repurposed to interfere with viral replication in some COVID-19 cases. Hints 1 Used in hospital settings for certain patients. 2 Inhibits viral RNA synthesis. 3 Originally developed for other viruses before COVID-19. 7 A diagnostic method that detects viral RNA from patient samples. Hints 1 Requires specialized laboratory equipment. 2 Amplifies genetic material to detectable levels. 3 Gold standard for diagnosing active infection in many guidelines. 8 A vaccine platform that uses messenger RNA to instruct cells to produce an immune target. Hints 1 Examples include vaccines developed against SARS-CoV-2. 2 Leads to production of an immune response without infection. 3 Encodes the viral antigen rather than the whole pathogen. 9 A basic epidemiological metric representing the average number of secondary cases from an infected individual in a fully susceptible population. Hints 1 Not a fixed value; depends on context. 2 Can change with interventions and population immunity. 3 Used to gauge contagiousness in the early phase of an outbreak.

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COVID-19: Molecular Entry Puzzle

Devinette

À propos de cette activité

Créé par

Téléchargez la version pour jouer sur papier

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COVID-19: Molecular Entry PuzzleVersion en ligne

par Mohammed Zahir Khan

A doorway on human cells that the virus seeks to open.

Hints

A simple act that helps stop germs from spreading.

Hints

A tiny invader with a crown-like appearance that started a global crisis.

Hints

A specific protein on my surface helps me attach to human cells and enter them.

Hints

I reside on the cell surface, acting as the doorway that SARS-CoV-2 uses to gain entry.

Hints

An antiviral drug repurposed to interfere with viral replication in some COVID-19 cases.

Hints

A diagnostic method that detects viral RNA from patient samples.

Hints

A vaccine platform that uses messenger RNA to instruct cells to produce an immune target.

Hints

A basic epidemiological metric representing the average number of secondary cases from an infected individual in a fully susceptible population.

Hints