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Urinary system

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Urinary system

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Urinary System what u need to know.

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Urinary systemVersion en ligne

Urinary System what u need to know.

par Yeslin Santos
1

body fastin vitamin calcitriol metabolic environment ECF pressure blood excess acid volume ions osmolarity base D water RBC toxins Gluconeogenesis ions solutes regulating regulating production blood erythropoietin internal wastes renin

* Removal of , , and from the
* Maintain the ? s :
* Regulate total and ( concentration of ) of the body
* Regulate concentrations of in ( ex . Na + , K + , Ca + , Cl - )
* Maintain - balance
* Hormone production ( for and for )
* Converts to ( its active form )
* during prolonged

2

Urethra Nephrons Ureters Kidneys Urinary bladder

* are major excretory organs
- are the functional excretory units
* is the temporary storage reservoir for urine
* transport urine from the kidneys to the bladder
* transports urine out of the bod y

3

hilu superior concave Ureters Convex nerves lumbar hilum Right blood renal sinus lymphatics Retroperitoneal vessels left

The Kidneys
* , in the region
* kidney is lower than the
* lateral surface , medial surface
* Renal leads to the renal
* , , , and enter and exit at the

4

Cortex calyx Renal Superficial Pelvis Minor Renal Medulla Column Renal Renal

: Contains bulk of nephron structures ; region of kidney

: Containing mostly
collecting ducts

: Runs between each medulla

: Cup shaped , encircles the apex of a pyramid

- Basin area of kidney , continuous with urete r

5

urine functional Nephrons cortex urine conserving interface Renal renal tubule 85% Juxtamedullary concentrated Bowman corpuscle loops capsule wate capillaries units 1 Nephrons medulla Glomerulus Cortical long

The Nephron :
Structural and that form
Each kidney contains about million nephrons

Two main parts :
- ( ) : a tuft of
- : begins as cup - shaped glomerular ( ? s ) surrounding the glomerulus


Two Classes
- : About of all nephrons , almost completely in cortex

- : Originate at - , that dip into the medulla ; allow for production of &

6

PCT cortical DCT recta juxtamedullary Vasa Peritubular capillaries

Two Classes
Cortical Nephrons :
associated with and of nephrons

Juxtamedullary Nephrons :
associated with the nephron loop of nephron s

7

arterioles afferent JGC walls blood cells NaCl glomerulus Macula Juxtaglomerular signal mesangial densa systemic loop afferent cells blood pressure cells macula chemical JGC ascending filtrate renin Extraglomerular tubule Complex cells arteriole nephron ascending communication distal convoluted densa concentrations Complex Granular arteriole Juxtaglomerular JGC pressure granular Complex chemoreceptor Juxtaglomerular formation mechanoreceptors

* ( ) : Region where portion of nephron loop lies against the that feeds the

* ( ) : Both the and cells are modified at point of contact

* ( ) helps to regulate rate of &

* ? modified cells of nephron loop ; packed beside granular cells ; cells that monitor of filtrate entering the

* ? found in ; act as , releasing when changes in occur

* ? lie between the nephron loop and arterioles ; allows between and via

8

high Nitrogenous 5% Abnormally 95% cleansing balancing pathology urine blood formation Chemically filtered urine wastes

* water and solutes

* : urea , uric acid , and creatinine

* Other normal solutes
Na + , K + , PO43 ? , and SO42 ? ,
Ca2 + , Mg2 + and HCO3 ?

* concentrations of any constituent may indicate

* and of the blood leads to ? is literally just !

9

Tubular secretion reabsorption Tubular filtration Glomerular

* : " dumping filtrate into the waste container "

* : " reclaiming what the body needs to keep "

* : " selectively adding to the waste container "

10

Net pressure formation Pressure solutes out Filtration solutes Hydrostatic water pressure filtrate Colloid i water outward osmotic inward

* is determined by the differences in and pressures

* of the glomerular capillaries ( HPgc ) aka glomerular BP , promotes , " the push " forcing and of blood

* of the glomerular capillaries ( OPgc ) , " the pull " by blood proteins keeping and

11

pressure acid chronic stones bacterial ureter calcium infection Kidney uric Ca2 urine magnesium pH pain

* form in renal pelvis
- Crystallized , , or salts
* Larger stones block , cause and in kidneys
* May be due to , retention , ? + in blood , ? of urin e

12

Micturition

: Urination or voidin g

13

urethral ANS nervous urethral detrusor internal sphincter syste ANS external sphincter somatic muscle

Three simultaneous events
* Contraction of by
* Opening of by
* Opening of by

14

180 150 24 0 metabolism output 8 cellular Urinalysis 1 diet consistancy 2 urinary Urinalysis 30 urine

* Blood composition depends on : , and

* In hours , million nephrons of the kidneys filter - liters of blood plasma ; resulting in . - liter of urine output daily
* In healthy individuals , kidneys maintain despite variation in diet and metabolic activity

* allows testing to determine substances present in a urine specimen ? this can be used to assess health of a patient

* must be done within minutes after urine is voide d

15

Color Transparency urine gravity of pH Odor Specific

* and

* ? slightly aromatic

* ranges from 4 . 5 - 8 . 0 ( average of 6 )

* is the relative weight of a specific volume of liquid compared with an equal volume of distilled water . The specific gravity of distilled water is 1 . 000 , because 1 ml weighs 1 gram .

16

Transparency yellow Color water pale blood amber urochrome drugs UT solutes clear bile foods

* and

* Should be and to in color , due to ( pigment metabolite of bilirubin )

* Color variations indicate the relative concentration of to in the urine

* Abnormal urine color may be due to certain , such as beets , various , , or

* Cloudy urine may indicate a

17

urine acidity vegetarian alkalinity disease infection Diet 0 Odor urine whole 8 urine ammonia urine wheat pH increase of odor protein 4 urine ash pH 6 tract pH diet urine odor urinary vegetables drugs Bacteria acid 5

* ? slightly aromatic
- action gives it an - like
- Some , and various processes alter the characteristic or .
Example : someone with uncontrolled diabetes mellitus makes urine smell fruity or acetone - like .

* ranges from . - . ( average of )
* can influence or
- A diet high in and raise the of . The foods that can
the are called foods .
- A ( alkaline ash diet ) increases the of the .
- A may also result in urine with a high pH .

18

1 water kidney gravity Specific precipitate distilled 1 solutes crystallize more 001 urinprober 1 ml specific less 000 volume 1 1 liquid equal hydrometer stones volume 030

* is the relative weight of a of compared with an of . The specific gravity of distilled water is . , because weighs gram .

- Measured using a /
- Urine weighs more because it has ? normal is . - . .

- High specific gravity = solutes
Limited fluid intake , fever , kidney inflammation

- Low specific gravity = solutes
Excessive water intake , diabetes insipidus or chronic renal failure

* If urine becomes excessively concentrated , some substances normally held in solution begin to or forming ( renal calculi ) .

19

collecting blood distal cell pathological blood Casts white ducts Hyaline red convoluted Hardened cell tubules

:
* cell fragments , formed in &
* , and casts
* Always indicate a conditio n

20

blood insulin High diabetes inadequate Glycosuri transport mellitus Glucosuria carbohydrate mechanisms sugar Glucose exceeded active levels

( ) :
* due to levels ; or can result when for glucose are temporarily
* Excessive intake
* Uncontrolled
* Aka

21

kidney trauma glomerulus big pregnancy protein exertion Albumin Pathological overabundant intake permeability Poisons Hypertension excessive Toxins increased

* - albumin in urine

- Normally albumin is too to pass through the ? so when it does you have an abnormally of the membrane .

- Nonpathological conditions :
, ,

- conditions usually events that damage the glomerular membrane
*
*
*
*

22

ketones metabolic starvation diabetes acid mellitu small acidosis abnormal bodies acid carbohydrates acetone ketone fat glucose hydroxybutyric beta diets larger

* Ketone Bodies ( Ketonuria ) :
Acetoacetic , - and are .

- Normally found in amounts in urine

- If amounts usually indicates processes are occurring . The result is .

- Expect to see this during or very low in ? inadequate food forces the body to use its stored .

- Finding both and usually indicates

23

Blood big rbc Red Cells pathology

* ( hematuria ) :
Indicates of the urinary tract ? are too to pass through glomerular pores

- Kidney stones
- Infection
- Tumors
- Physical trauma to urinary organ s

24

hemolysis Hemoglobin RBCs

* ( Hemoglobinuria ) in urine as a result of ( bursting ) of

* Indicates
- Hemolytic anemias
- Transfusion reactions
- Burns
- Venomous snake bites
- Renal diseas e

25

Bile trac yellow foam pathology Blood urinary liver Nitrites urine infection infection shaken White Pigments bacterial bladder Cells inflammation

*
- May indicate a ( E . coli )
- Valuable for early indicators of

* ( Bilirubinuria ) bilirubin in urine ( bile pigments )
Usually indicates
- hepatitis
- cirrhosis
- bile duct blockage
Usually forms when urine is

* ( Pyuria ) presence of white blood cells in ( pus )
- Indicates of

26

Glomerulonephritis insipidus Diabetes Pyelonephritis Gonorrhea Diabetes mellitus

* - kidney infection

* - " glomerular disease " acute inflammation of the kidney , typically caused by an immune response

* - sexually transmitted bacterial infection

* - diabetes - too much sugar in the blood

* - rare - caused by a deficiency of the pituitary hormone ADH ( vasopressin ) which regulates kidney function .

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