Relier Pairs HIV Drug Mechanisms of ActionVersion en ligne Match the HIV drug class with its mechanism of action par Ethan Lentz 1 Nucleoside reverse transcriptase inhibitors 2 CYP3A4 inhibitors (protease inhibitor boosters) 3 Integrase inhibitors 4 Non-nucleoside reverse transcriptase inhibitors 5 HIV Protease inhibitors Acts as a substrate for reverse transcriptase, inserting into viral DNA and blocking replication at 3'-OH Bind to the active site of HIV proteases preventing the creation of new viral particles Inhibit destruction of protease inhibitors by host metabolism Inhibits HIV integrase enzyme preventing insertion of viral cDNA into the host genome Allosterically bind to reverse transcriptase to reduce molecular motion in the enzyme and inhibit its function
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