Compléter GluconeogenesisVersion en ligne Gluconeogenesis par kenneth thomas 1 cytoplasm pyridoxal triglycerides mitochondria anaerobically glucose B6 insulin phosphate oxaloacetate transmination oxaloacetate cortisol glucagon glycerol Gluconeogenesis is the creation of from other products to meet body needs It occurs mainly in the , but some reactions occur in the ( pyruvate to to malate ) The malate then crosses the mitochondrial membrane where it is converted back into . This reaction is stimulated , when glucose is all gone in the blood stream , by both and it is inhibited by , when glucose is abundant Primary precursors to this reaction include , which is supplied from the breakdown of in the fatty tissues . Lactate is supplied when the muscles function . And amino acids when necessary . In order to be used , amino acids must undergo a reaction facilitated by the enzyme that is a derived from vitamin .