The Pathophysiology Puzzle 2 (Stroke, CAncer, NSTEMI. STEMI, HTN)Version en ligne Test your knowledge of cancer pathophysiology by correctly ordering key concepts related to its development and progression. par Teisha Vaughn 1 Order the elements based on the sequence of events in the progression of cancer development. Invasion of surrounding tissues Progression to malignancy Metastasis to distant sites Angiogenesis to support tumor growth Initiation of genetic mutations Promotion of cell proliferation 2 Order the elements based on the sequence of events leading to NSTEMI, from initial trigger to final outcome. Plaque rupture or erosion Partial occlusion of the coronary artery Formation of a thrombus Platelet activation and aggregation Myocardial ischemia Cellular injury and necrosis 3 Order the elements based on the sequence of physiological events that occur during a STEMI, from the initial trigger to the final consequences. Ischemia of myocardial tissue Myocardial cell injury Release of inflammatory mediators Complications such as heart failure or arrhythmias Coronary artery occlusion Necrosis of myocardial tissue 4 Order the elements based on the sequence of pathophysiological events leading to a cerebrovascular accident. Release of excitatory neurotransmitters Inflammatory response and cell death Decreased blood flow to the brain Initial vascular occlusion or rupture Potential recovery or chronic deficits Ischemic or hemorrhagic damage to brain tissue