Froggy Jumps Gene Therapy Vector ChallengeVersion en ligne Test your knowledge on the types of vectors used in gene therapy! par Sharaf Sultana 1 What is a common viral vector used in gene therapy? a Bacteriophage b Plasmid c Adenovirus 2 Which vector is known for stable gene integration? a Adenovirus b Lentivirus c Adeno-associated virus 3 What type of vector is often used for delivering small RNA molecules? a Lentiviral vector b Adenoviral vector c Retroviral vector 4 Which vector has a low immunogenicity and can persist in host cells? a Lentivirus b Herpes simplex virus c Adeno-associated virus 5 What is a key advantage of using plasmid vectors? a Ease of production b High efficiency c Stable integration 6 Which vector is derived from the herpes simplex virus? a Lentivirus b Herpes viral vector c Adenovirus 7 What is a disadvantage of using retroviral vectors? a High immunogenicity b Insertional mutagenesis risk c Low transduction efficiency 8 Which vector is commonly used for cancer gene therapy? a Oncolytic virus b Adeno-associated virus c Lentivirus 9 What type of vector is best for transient expression? a Retroviral vector b Lentiviral vector c Adenoviral vector 10 Which vector is often used for gene editing applications? a Adeno-associated virus b Bacteriophage c Plasmid 11 What does AAV stand for? a Adenovirus-associated vector b Adeno-associated virus c Adeno-viral agent 12 AAV is commonly used in which field? a Vaccine development b Cancer treatment c Gene therapy 13 What type of virus is AAV classified as? a Retrovirus b Parvovirus c Herpesvirus 14 AAV requires which virus for replication? a Adenovirus b Herpesvirus c Bacteriophage 15 What is a key feature of AAV in gene therapy? a Non-pathogenic b Highly pathogenic c Immunogenic 16 Which serotype of AAV is commonly used in research? a AAV2 b AAV5 c AAV8 17 AAV can integrate into which part of the host genome? a Plasmids b Mitochondria c Chromosome 19 18 What is the typical size of AAV genomes? a 4.7 kb b 2.5 kb c 10 kb 19 AAV vectors are often used to deliver what? a Antibodies b Proteins c Therapeutic genes 20 What is a major advantage of AAV vectors? a Short-term expression b Long-term expression c Rapid degradation 21 What is a retrovirus? a A type of bacteria. b A virus that uses RNA as its genetic material. c A virus that uses DNA as its genetic material. 22 Which enzyme is crucial for retrovirus replication? a RNA polymerase. b Reverse transcriptase. c DNA polymerase. 23 What disease is most commonly associated with HIV, a retrovirus? a Diabetes. b AIDS. c Cancer. 24 How do retroviruses integrate into the host genome? a By using helicase enzyme. b By using ligase enzyme. c By using integrase enzyme. 25 Which of the following is a common retrovirus in animals? a Feline leukemia virus. b Influenza virus. c Ebola virus. 26 What type of genetic material do retroviruses possess? a Single-stranded RNA. b Double-stranded DNA. c Double-stranded RNA. 27 What is the primary method of HIV transmission? a Airborne particles. b Contaminated food. c Through bodily fluids. 28 What is the role of the envelope in retroviruses? a To protect the virus and aid in cell entry. b To store genetic material. c To replicate RNA. 29 Which retrovirus is known for causing cancer in animals? a Rous sarcoma virus. b Hepatitis B virus. c Zika virus. 30 What is a common treatment for HIV infection? a Antibiotics. b Antiretroviral therapy. c Vaccination. 31 What is a lentivirus? a A type of retrovirus that can infect dividing and non-dividing cells. b A type of fungi found in soil. c A bacteria that causes infections. 32 Which disease is commonly associated with lentiviruses? a HIV/AIDS. b Tuberculosis c Influenza 33 What is the primary method of transmission for HIV, a lentivirus? a Through bodily fluids. b Airborne transmission c Contaminated water 34 Lentiviruses are known for their ability to integrate into which part of the host cell? a Mitochondria b The host genome. c Cytoplasm 35 Which of the following is a characteristic of lentiviruses? a They cause immediate symptoms. b They can establish long-term infections. c They only infect plants. 36 What is the structure of lentiviruses primarily composed of? a Carbohydrates and minerals b RNA and proteins. c DNA and lipids 37 Which animal is a natural reservoir for some lentiviruses? a Primates. b Birds c Reptiles 38 What type of vaccine is being researched for lentivirus prevention? a Inactivated vaccines b Viral vector vaccines. c Live attenuated vaccines 39 Lentiviruses can be used in gene therapy due to their ability to: a Deliver genetic material into cells. b Replicate without a host c Cause cell death 40 What is the role of the envelope protein in lentiviruses? a To destroy host DNA b To facilitate entry into host cells. c To replicate viral RNA 41 What type of virus is adenovirus? a DNA virus b Retrovirus c RNA virus 42 Which disease is commonly associated with adenovirus? a Influenza b HIV c Respiratory infections 43 How is adenovirus primarily transmitted? a Insect bites b Respiratory droplets c Blood transfusion 44 What is a common symptom of adenovirus infection? a Nausea b Fever c Rash 45 Adenoviruses can cause conjunctivitis. What is this condition? a Pink eye b Stomach flu c Ear infection 46 Which age group is most affected by adenovirus infections? a Elderly b Adults c Children 47 Can adenoviruses be used in gene therapy? a Yes b No c Only in animals 48 What is the structure of adenovirus? a Spherical b Helical c Icosahedral 49 What is the incubation period for adenovirus infections? a 15 to 30 days b 2 to 14 days c 1 to 3 days 50 Is there a vaccine available for adenovirus? a Yes, for military personnel b No, there is none c Yes, for everyone
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