Relier Pairs Cholesterol pharmacologyVersion en ligne Cholesterol pharmacology par Ashleigh Pell 1 statin indication 2 What statins do, and where 3 statin with less drug interactions 4 What does the enzyme HMG-CoA do? 5 most potent statin 6 statin warning 7 with less cholesterol synthesis, what does the liver do? 8 standard statin 9 statin side effects Grapefruit inhibits cytochrome P450, increasing statin bioavailability. simvastatin atorvastatin inhibit HMG-CoA reductase in the liver myalgia/headache/GI symptoms pravastatin high lipids / LDL increases hepatic synthesis of cholesterol increases the uptake of low-density lipoprotein (LDL) from the blood 1 ezetimisbe side effect 2 fenofibrate causes lipolysis because 3 Fenofibrate indication 4 fenofibrate activates 5 Alirocumab inhibits 6 Alirocumab side effects 7 fenofibrate caution 8 alirocumab indication 9 fenofibrate contra-indication 10 ezetimibe inhibits 11 fenofibrate side effects PPARα's genes code for peroxisomes which participate in lipolysis GI upset/vomiting weakness/GI upset/headaches gall bladder disease, pancreatitis nuclear receptor PPARα which begins gene transcription and translation high serum triglycerides myotoxicity if improper dose or renal impairment. intestinal cholesterol absorption inhibits PCSK9, a liver protein that regulates/breaks down LDL receptors familial hypercholesterolaemia, high risk, statins and ezetimibe ineffective flu-like symptoms
Créer jeu