Relier Pairs Cholesterol pharmacologyVersion en ligne Cholesterol pharmacology par Ashleigh Pell 1 statin warning 2 with less cholesterol synthesis, what does the liver do? 3 most potent statin 4 standard statin 5 statin with less drug interactions 6 What statins do, and where 7 statin indication 8 statin side effects 9 What does the enzyme HMG-CoA do? myalgia/headache/GI symptoms increases hepatic synthesis of cholesterol simvastatin pravastatin inhibit HMG-CoA reductase in the liver high lipids / LDL increases the uptake of low-density lipoprotein (LDL) from the blood atorvastatin Grapefruit inhibits cytochrome P450, increasing statin bioavailability. 1 fenofibrate contra-indication 2 Alirocumab inhibits 3 alirocumab indication 4 Alirocumab side effects 5 fenofibrate causes lipolysis because 6 fenofibrate side effects 7 fenofibrate activates 8 Fenofibrate indication 9 ezetimisbe side effect 10 ezetimibe inhibits 11 fenofibrate caution intestinal cholesterol absorption myotoxicity if improper dose or renal impairment. flu-like symptoms PPARα's genes code for peroxisomes which participate in lipolysis high serum triglycerides GI upset/vomiting inhibits PCSK9, a liver protein that regulates/breaks down LDL receptors weakness/GI upset/headaches gall bladder disease, pancreatitis familial hypercholesterolaemia, high risk, statins and ezetimibe ineffective nuclear receptor PPARα which begins gene transcription and translation
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