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Fill in the Blanks: Krebs Cycle

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Test your knowledge of the Krebs cycle by filling in the missing words in this interactive game!

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Fill in the Blanks: Krebs CycleVersion en ligne

Test your knowledge of the Krebs cycle by filling in the missing words in this interactive game!

par Bio Innovators
1

Krebs cycle matrix transport chain NADH Tricarboxylic acid electron FADH2

is also known as Citric acid cycle or cycle . It occurs in the of mitochondria to provide in the form of and that are used in electron .

2

Citrate isocitrate pyruvate oxidation oxaloacetate, OAA CoA removal Isomerization rearranged citrate addition Condensation

1 .
Acetyl - CoA from removes group . The remaining acetyl combines with to form .

2 .
is then to its isomer , by the of one water molecule and of one water molecule .

3

CO2 H decarboxylation ketoglutarate transferring NAD reduced 5-carbon

3 . Oxidative decarboxylation
Isocitrate loses a molecule of , forming a molecule ( ) . The remaining 5 - carbon is oxidized into ? - , by their electrons and + to NAD + . + is to NADH + H + .

4

oxidized Coenzyme A CO2 ketoglutarate NADH 4C molecule succinyl CoA

4 . Oxidative decarboxylation
? - lose a molecule of forming a 4C molecule . The remaining is before combining with , to form . NAD + is reduced to + H + .

5

fumarate GTP succinate ATP Substrate level phosphate group CoA GTP FAD FAD FADH Succinate phosphorylation energy two hydrogen atoms ADP

5 . phosphorylation
Succinyl - CoA loses and converted to . The released is used in the of GDP to form . then transfer its to to form .

6 . Oxidation
is oxidized to , by transferring to . is reduced to .

6

NADH malate oxaloacetate water molecule oxidized rearranged Malate Reduction Fumarate regenerated

7 . Hydration
is into by addition of one .

8 . Oxidation
is . of NAD + to + H + occurs and is .

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