Relier Pairs NUR 341 Mechanism of action 1Version en ligne Match par Tamara Garcia 1 Furosemide 2 Cephalexin 3 Heparin 4 Amlodipine 5 Atorvastatin Simvastatin 6 Acetaminophen/codeine Acetaminophen/oxycodone Hydrocodone/Acetaminophen Hydromorphone 7 Clopidogrel Inhibits bacterial cell wall synthesis by binding to one or more of the penicillin-binding proteins (PBPs). Inhibits reabsorption of sodium and chloride in the ascending loop of Henle and proximal and distal renal tubules, interfering with the chloride-binding cotransport system, thus causing its natriuretic effect. Blocks the P2Y12 component of ADP receptors on the platelet surface, which prevents activation of the GPIIb/IIIa receptor complex, thereby reducing platelet aggregation. Inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, the rate-limiting enzyme in cholesterol synthesis; helps reduce inflammation at the site of the coronary plaque, inhibits platelet aggregation, and has anticoagulant effects. Inhibits calcium ion from entering the “slow channels” or select voltage-sensitive areas of vascular smooth muscle and myocardium during depolarization, producing a relaxation of coronary vascular smooth muscle and coronary vasodilation; it also increases myocardial oxygen delivery. Inhibits pain pathways in the CNS. Potentiates the action of antithrombin III and thereby inactivates thrombin and prevents the conversion of fibrinogen to fibrin.
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