Relier Pairs Week 1 CardiologyVersion en ligne Describe the epidemiology of acute coronary syndromes and stable coronary artery disease Discuss the prognosis and impact of ischaemic heart disease on daily life. Describe how good management can improve both aspects Explain how the cardiovascular system adapts to exercise par Hannah Barton 1 What is coronary artery disease an umbrella term for? 2 What is increased contractility of the heart a result of? 3 How many patients experiencing an acute MI die before reaching the hospital? 4 What is increased preload a result of? 5 How can stable and unstable angina be differentiated from the history? 6 How is blood pressure calculated? 7 Why are blood pressure changes minimal during exercise? 8 How is reperfusion therapy useful in MI? 9 Why must splenic contraction increase during exercise? 10 How can stable angina progress to unstable angina (acute coronary syndrome) 11 Aspirin for secondary prevention can reduce risk of MI, stroke or vascular death by how much…? 12 What is variant angina? 13 What are some risk factors for the acute coronary syndromes? 25% Angina without the presence of physical plaques; caused by intense vasospasm Up to 30% of RBCs are stored here and so increased contraction ejects more of these into blood stream to transport oxygen Reduces infarct size and can help to prevent death from heart failure and ventricular arrhythmias 33% Conditions involving atherosclerosis restricting blood flow to the heart, causing ischaemia Cardiac output x systemic vascular resistance Whether or not they are provoked by exercise The plaque narrowing the lumen ruptures causing platelet aggregation, thrombus formation and unopposed vasoconstriction Increased use of skeletal muscle pumps and peripheral vasoconstriction means Increased sympathetic nervous system activity Ageing, hypertension, hypercholesteremia, smoking, obesity Reduced pulmonary and systemic vascular resistance to blood flow
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