classification thiazolidinediones
Side effects metformin
metformin NC
Side effects of Pioglitazone Rosiglitazone
sulfuonylureas classification
glyburide glipizide MOA
MOA metformin
Side effects glyburide glipizide
MOA Pioglitazone Rosiglitazone
classification biguanide
act in beta cells in the pancreas to stimulate increase in insulin production and increase number of insulin receptors
decreases insulin resistance decreases glucose output in the liver
decrease absorption of glucose decrease glucose production increase insulin sensitivity by increase uptake in tissue
Pioglitazone Rosiglitazone
metformin
risk of lactic acidosis
Glyburide Glipizide
EDEMA liver failure CHF weight gain
hypoglycemia weight gain contraindicated with sulfa allergy
GI side effects, N/V/D weight lose contraindicated if impaired liver/renal function little risk for hypoglycemia
