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1. Pharmacologic treatment of epididymitis may include the following:
2. In addition to antibiotics (except in viral epididymitis), the mainstays of supportive therapy for acute epididymitis and orchitis are as follows:
3. Surgical options include the following:
4. Complications associated with acute epididymitis and bacterial orchitis include the following:

Scrotal support and elevation

Cutaneous fistulization from rupture of an abscess through the tunica vaginalis (seen especially in tuberculosis)

Analgesics, including nerve blocks

Avoidance of urethral instrumentation

When treating epididymitis secondary to Chlamydia trachomatis or Neisseria gonorrhoeae, treatment of all sexual partners

Testicular infarction: Cord swelling can limit testicular artery blood flow

Reduction in physical activity

Epididymectomy: Typically reserved for refractory cases

Scrotal abscess and pyocele

Sitz baths

Orchiectomy: Indicated only for patients with unrelenting epididymal pain

Anti-inflammatory agents

Ice packs

Epididymotomy: Infrequently performed in patients with acute suppurative epididymitis

In chronic epididymitis, a 4- to 6-week trial of antibiotics effective against bacterial pathogens (especially chlamydiae)

Fertility problems

Recurrence, chronic epididymitis, and orchialgia

Skeletonization of the spermatic cord via subinguinal varicocelectomy: Performed in rare cases of refractory pain due to chronic epididymitis and orchialgia

Testicular atrophy

In prepubertal patients with epididymitis, antibiotic therapy only for young infants and those with pyuria or positive urine culture findings