Mixed
connective
-
tissue
disease
(
MCTD
)
is
a
disorder
with
features
____________________
systemic
sclerosis
(
SSc
)
,
lupus
erythematosus
,
and
polymyositis
.
U1
-
ribonucleoprotein
(
RNP
)
antibodies
____________________
a
specific
marker
of
the
disease
.
MCTD
is
____________________
a
distinct
syndrome
and
should
not
be
confused
with
____________________
connective
-
tissue
disease
overlap
syndromes
with
features
of
____________________
connective
-
tissue
diseases
.
The
course
of
MCTD
is
chronic
____________________
usually
milder
than
other
connective
-
tissue
diseases
.
Although
MCTD
is
a
distinct
clinical
____________________
,
a
subgroup
of
patients
may
evolve
into
____________________
another
connective
-
tissue
disease
.
