Anhalt
et
al
first
____________________
paraneoplastic
pemphigus
in
1990
.
The
authors
____________________
5
patients
with
underlying
neoplasms
who
____________________
oral
erosions
and
bullous
skin
eruptions
.
Skin
biopsy
samples
showed
both
suprabasal
acantholysis
____________________
interface
dermatitis
.
Direct
immunofluorescence
(
DIF
)
testing
and
indirect
immunofluorescence
(
IDIF
)
testing
revealed
intraepidermal
intercellular
staining
with
immunoglobulin
G
(
IgG
)
;
DIF
testing
also
____________________
deposition
of
complement
____________________
the
dermoepidermal
junction
(
see
the
image
below
)
.
By
immunoprecipitation
,
target
antigens
were
identified
from
skin
extracts
with
molecular
weights
of
250
,
230
,
210
,
and
190
kd
.
Since
then
,
many
patients
with
paraneoplastic
pemphigus
have
been
____________________
,
and
patients
previously
believed
____________________
have
other
diseases
have
been
retrospectively
____________________
.
