Systemic
sclerosis
(
SSc
)
is
a
systemic
connective
tissue
disease
.
Characteristics
____________________
systemic
sclerosis
include
essential
vasomotor
disturbances
;
fibrosis
;
subsequent
____________________
of
the
skin
(
see
the
image
below
)
,
subcutaneous
tissue
,
muscles
,
and
internal
____________________
(
eg
,
alimentary
tract
,
lungs
,
heart
,
kidney
,
CNS
)
;
and
immunologic
disturbances
accompany
these
____________________
.
In
one
survey
one
quarter
of
patients
with
Raynaud
phenomenon
not
____________________
the
1980
American
College
of
Rheumatology
classification
criteria
____________________
reclassified
as
having
systemic
sclerosis
using
the
2013
American
College
of
Rheumatology
/
European
League
Against
Rheumatism
(
EULAR
)
criteria
.
