However, whether a diagnosis of metabolic syndrome provides more useful information than its individual components regarding cardiovascular risk is greatly controversial.
is associated with endothelial dysfunction and atherosclerosis resulting in an increased risk of cardiovascular disease (CVD) and type 2 DM. The main utility of diagnosing metabolic syndrome is the identification of people at high risk of CVD beyond LDL-cholesterol levels.
No known common cause unifies its components. The condition reflects the sedentary lifestyle, overnutrition, and resultant excess adiposity of the modern world.
originally described by Reaven in 1988 as "syndrome X" or "insulin resistance syndrome", is a cluster of common abnormalities, including insulin resistance, impaired glucose tolerance, abdominal obesity, reduced HDL-cholesterol levels, elevated triglycerides, and hypertension.
