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An acrochordon is a small , soft , common , benign , usually pedunculated neoplasm that is ____________________
particularly in persons who are obese . It is usually skin colored or hyperpigmented , and it may ____________________
as surface nodules or papillomas ____________________ healthy skin . Most acrochordons vary in size from 2 - 5 mm in
diameter , although larger acrochordons up to 5 cm in diameter are sometimes evident . The most
frequent localizations are the neck ____________________ the axillae , but any skin fold , including the groin , may be
affected .
Birt - Hogg - Dube ( BHD ) syndrome is a rare autosomal dominant genodermatosis characterized ____________________ skin
tumors , including multiple fibrofolliculomas , trichodiscomas , and acrochordons . These patients tend
to develop renal and colonic carcinomas . ____________________ defective gene in BHD syndrome has been ____________________
and is ____________________ of being a tumor suppressor gene . Several mutations of the BHD gene have been
reported . All skin lesions in the syndrome may actually represent fibrofolliculomas ____________________ in various
planes of section .