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1. Classification: Ergot derivatives
2. Classification: Triptans
3. Classification: Benzodiazepines
4. Classification: Barbiturates/anxiolytics
5. Classification: Tricyclic Antidepressants (TCAs)

Indications: tx of anxiety disorders, alcohol w/drawal, hyperexcitability/agitation, preop relief of anxiety/tension.

Indications: Tx for acute migraines & cluster HAs

Action: Inhibits presynaptic reuptake of norepi & serotonin; anticholinergic at CNS & peripheral receptors, sedating.

Prototype: Diazepam (Valium)

Indication: tx of migraines or vascular HAs

Prototype: Ergotamine (Ergomar)

Prototype: Imipramine (Tofranil)

Prototype: Sumatriptan (Imitrex)

Prototype: Phenobarbital (generic)

Action: Blocks alpha-adrenergic & serotonin receptor sites in brain: constriction of cranial vessels.

Indication: relief of depression symptoms

Action: binds to selective serotonin receptor sites to cause vasoconstriction of cranial vessels.

Indications: sedation; tx of insomnia; tx of seizures; preanesthetic.

Action: Acts in limbic system & RAS to potentiate effects of GABA, an inhibitory neurotransmitter; may act in SC & suprasternal sites to produce muscle relaxation.

Action: Inhibits conduction in ascending RAS; depresses cerebral cortex; alters cerebellar function; depresses motor output