Itraconazole-oral (200-400 mg/d) 6-18 mo
Look at grains within the infected tissue, Need ID to select treatment
cryptococcus yeast
Hard, nontender, subcutaneous nodule Progresses to ulcers along lymphatics
Sporotrichosis
candidia yeast
Inhalation->progressive lung disease->meningitis
Tropical
Puncture into skin- Follow up for relapse for years
Mycetoma
Yeast with capsule
Most common form of fungal meningitis- Immunocompromised
Amphotericin B
Chromoblastomycosis
Worldwide- soil, sphagnum moss or decaying wood
Localized trauma, Small papule to progression over years
Lesions follow puncture wounds, Progress to ulcers