Doxorubicin
Vincristine
Etoposide
Cyclophosphamide
Hydroxyurea
Pembrolizumab
Rituximab
Gemcitabine
Methotrexate
Bleomycin
Erlotinib
Bevacizumab
Imatinib
Cisplatin
Irinotecan
Paclitaxel
Inhibits dihydrofolate reducatse
Inhibits ribonucleotide reductase & DNA polymerase
Tyrosine Kinase - EGFR inhibitor
Inhibits topoisomerase I & causes double strand DNA breaks
Inhibits microtubule formation
Inhibits topoisomerase II
Cross links DNA, inhibiting synthesis
Free radicals break DNA & Topoisomerase II inhibitor
Monoclonal Ab causes CD20+ B-Cell apoptosis
Monoclonal Ab blocks VEGF
Promotes microtubule formation then prevents their degradation
Monoclonal Ab Inhibits PD-1
Cross links DNA, inhibiting synthesis
BCR-ABL - Tyrosine Kinase Inhibitor
Free radicals break DNA
Inhibits ribonucleotide reductase & increases HbF levels