2.
The concentration of a drug needed to cause half the maximum possible effect
A
RE45
B
WE45
C
EC50
3.
What is Potency of a drug?
A
The speed with which the drug travels
B
Amount of drug required to give a certain response.
C
The action it performs within the body
4.
Effective dose
A
The dose that produces the desired effectin 50% of all who use the drug
B
The dose that produces a toxic effect
C
The dose that causes death
5.
Lethal dose
A
The dose that produces a toxic
B
The dose that produces the desired effectin 50% of all who use the drug
C
The dose that causes death
6.
Toxic dose
A
The dose that produces a toxic effect
B
The dose that produces the desired effectin 50% of all who use the drug
C
The dose that causes death
7.
What is Therapeutic Window?
A
Ratiobetween the doses causingadverse effects and thoserequired to produce thebeneficial effects
B
Drug activation
C
Number of probabilities of a drug
8.
What is Maximal Tolerated Dose?
A
Availability of a drug
B
H ighest dose of drug thatcan be administeredwithout the development ofdoce related adverseeffects
C
The amount of supply within the body
9.
What is the antagonist and agonist for Angina Pectoris?
A
Atropine- Acetylcholine
B
Atenolol- Noradrenaline
C
Naloxone- Morphine
10.
What is the antagonist and agonist for peptic ulcer disease?
A
Cimetidine - Histamine
B
Atenolol - Noradrenaline
C
Naloxone - Morphine
11.
what is the dissociation constant (concentration of free drug at which half of all receptors are occupied) Is it a measure of affinity for the receptor?
A
Ed
B
Kd
C
Log
12.
What is the potency of a drug?
A
Amount of drug required to give a certain response.
B
How quickly the drug works
C
The effectiveness of the drug
13.
What does the intensity of action of a drug depend on?
A
From the action of the drug
B
The composition of a drug
C
Affinity of the drug for receptors: if the affinity increases, the effect increases.
14.
What is the intrinsic activity of the drug?
A
maximum efficacy
B
The duration of the drug
C
The stability of a drug
15.
MTC
A
Minimum efect
B
Minimum tolerance
C
Minimum toxic concentration
16.
MEC
A
Minimum toxic concentration
B
Minimum effectiveconcentration
C
Minimum efect
17.
Relationship established between the dose of a drug and its clinical response
A
Drug reaction curve
B
Relationship of the drug
C
Dose response curve
18.
Dose-effect
A
.
B
Correspondence between exposure dose and proportion of individuals
C
Exposure dose and the magnitude of a specific effect in a given individual
19.
Dose-response
A
correspondence between the dose of exposure
B
.
C
Correspondence between exposure dose and proportion of individuals
20.
Therapeutic or toxic response generated by drugs is attributed to structural interactions with macromolecules.
and the modification of the functional activity of these
